Classes Of Antibiotics

Classes of Antibiotics
The major classes of antibiotics overwhelm the following:
1. ?-Lactams
2. Aminoglycosides
3. Quinolones
4. Glycopeptides
5. Lincosamides
6. Macrolides
7. Oxazolidinoes
8. Streptogramins
9. Tetracyclines

Beta-lactams
Beta-lactams refers to all the antibiotics that contain the beta-lactam ring. They sign bacterial penicillin binding proteins thereby disrupting the synthesis of the peptidoglycan layer of bacterial cell walls. Antibiotics included in this class are listed below.
* Sulphonamides: These include Sulphamethizole, Sulphamethoxazole, Sulphadiazine, Cotrimoxazole and Trimethoprim. These antibiotics inhibit the synthesis of folate, thus preventing bacteria from synthesizing nucleic acids.
* Penicillins: These include Penicillin G, Penicillin V, Aminopenicillins (Ampicillin), Amoxicillin, penicillinase-resistant penicillins (Oxacillin), extensive spectrum penicillins (Piperacillin), co-drug penicillins (amoxicillin/clavulanate, ampicillin/sulbactam, piperacillin/tazobactum & ticarcillin/clavulanate).
* Monobactams: Aztreonam is included in this class.
* Carbapenems: This class is considered the ultimate of the beta-lactams and includes Imipenem/Cilastatin, Meropenem, Ertapenem, and Doripenem.




* Cephalosporins:
* First propagation works thoroughly against gram positive infections. Cefalothin, Cephalexin, and Cefadroxil are within this class.
* routine propagation has less(prenominal) gram positive activity and an improve gram negative activity. Cefuroxime, Cefaclor, and Cefprozil are within this class.
* Third generation have an improved gram negative coverage (except Psedomonas) and less gram positive coverage. Ceftriaxone, Ceftazidime, Cefixime, Cefdinir, Cefditoren, Cefotaxime, Cefpodoxime, and Ceftibuten are within this class.
* Fourth generation works well against Pseudomonal infections and includes the antibiotic, Cefepime.

Aminoglycosides
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