Dr. Patrick J. Arpino used the metaphor of the unlikely descent between a fish and a bird to attract the melding of the two distinctly different techniques of potbelly spectrometry and fluid chromatography. The bird from the air being the lot spectrometer which requires the analyte to be in a vapor mannikin in entrap to be analyzed. The fish from the sea is limpid chromatography, a technique that results in the separation of comp 1nts utilizing a liquid. It is improbable and difficult for these brute species to develop together as it was LC and MS. These two unlikely partners come together to produce unmatched of analytical chemistrys most powerful tools. Liquid Chromatography- Mass Spectrometry (LC-MS) is one of the so-called hyphenated instruments. This paper leave discuss the process of liquid chromatography, the types of interfaces between liquid chromatography apparatus and the mass spectrometer, and the applications and benefits of LC-MS. The operation and characteristics of the mass spectrometer will not be discussed in detail.
In describing the operation of liquid chromatography, the processes of normal phase, reversed phase, ion exchange and ion chromatography, and coat exclusion chromatography will each be discussed to indicate the total range of applicability. For each of these processes the process will be outlined, the phase chemistry will be detailed and the benefits of each will be displayed. Once the analyte has been separated into individual components by one of these processes the components move to the mass spectrometer to be analyzed. What brings the chromatography step and the mass spectrometer together is not an insignificant concern. This interface is by chance the most integral part of the instrument. There are many a(prenominal) types of interface technology that can range from having a broad(a) application to having a dedicated use. The technologies that will be presented are, woful belt...If you want to get a full essay, order it on our website: Ordercustompaper.com
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